ERG Off-Effects Produced by Short Duration Stimuli

Abstract
Variable duration square wave pulses of 633-nm light were used to produce electroretinograms (ERG) in a human subject. When the stimuli were presented on a white light background, the records obtained for stimulus durations > 70 ms showed a clearly separated off-response, while those of shorter durations did not. By subtracting a common on-effect from the ERG produced by short duration stimuli, the previously unseen off-effect was isolated from records produced by stimulus pulses as short as 5 ms. Apparently the marked increase in b-wave amplitude associated with these short duration stimuli can be attributed to an interaction between on and off components of the ERG.

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