Toxic and allergic manifestations of antimicrobials
- 1 September 1978
- journal article
- research article
- Published by Taylor & Francis in Postgraduate Medicine
- Vol. 64 (3) , 157-167
- https://doi.org/10.1080/00325481.1978.11714927
Abstract
All antimicrobial drugs may produce toxic and allergic reactions. Penicillins and cephalosporins cause the greatest number of allergic reactions and should not be used for treatment of minor infections in patients with a history of an adverse reaction. If no alternative antibiotic will suffice for treatment of a serious infection, skin testing is necessary. Two commonly used antimicrobials, clindamycin and isoniazid, can have potentially fatal toxic effects.Keywords
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