Yersinia pseudotuberculosis Produces a Cytotoxic Necrotizing Factor
- 1 May 2002
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 70 (5) , 2708-2714
- https://doi.org/10.1128/iai.70.5.2708-2714.2002
Abstract
Cell extracts from Yersinia pseudotuberculosis induced multinucleation in HEp-2 cells in a manner similar to the effect caused by Escherichia coli cytotoxic necrotizing factor (CNF). The activity was not dependent on the Yersinia 70-kb virulence plasmid, and the activity was not inhibited by antibodies capable of neutralizing E. coli CNF type 1. The nucleotide sequence of the Yersinia cnf gene was 65.1% identical to the E. coli cnf gene.Keywords
This publication has 40 references indexed in Scilit:
- Genome sequence of Yersinia pestis, the causative agent of plagueNature, 2001
- Epitope Mapping of Monoclonal Antibodies Capable of Neutralizing Cytotoxic Necrotizing Factor Type 1 of Uropathogenic Escherichia coliInfection and Immunity, 2001
- The Yersinia Protein Kinase A Is a Host Factor Inducible RhoA/Rac-binding Virulence FactorPublished by Elsevier ,2000
- Cytotoxic Necrotizing Factor Type 1 of Uropathogenic Escherichia coli Kills Cultured Human Uroepithelial 5637 Cells by an Apoptotic MechanismInfection and Immunity, 2000
- The Rho-deamidating Cytotoxic Necrotizing Factor 1 fromEscherichia coli Possesses Transglutaminase ActivityJournal of Biological Chemistry, 1998
- The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cellsMolecular Microbiology, 1997
- Basic Local Alignment Search ToolJournal of Molecular Biology, 1990
- Basic local alignment search toolJournal of Molecular Biology, 1990
- Production of cytotoxin VT in enteropathogenic and non-enteropathogenic Eschericha coli strains of porcine originFEMS Microbiology Letters, 1985
- Some Characteristics of a Heat-labile Toxin from Pasteurella pseudotuberculosisThe Journal of Infectious Diseases, 1969