Enzymatic hydrolysis of (di)methacrylates and their polymers
- 1 June 1990
- journal article
- research article
- Published by Wiley in European Journal of Oral Sciences
- Vol. 98 (3) , 261-267
- https://doi.org/10.1111/j.1600-0722.1990.tb00971.x
Abstract
Di- and monomethacrylates hydrolyze to methacrylic acid and the alcohol part at neutral pH catalyzed by an unspecific esterase (hydrolase) and by enzymes in saliva. The rate constants of the enzymatic hydrolysis of various (di)methacrylates increase in the following order: HPMA < BISGMA < LAMA < DECMA < TEGDMA < UEDMA < DEGDMA. Esterase added to aqueous slurries of various powders made of polymerized BISGMA/TEGDMA-mixtures gave rise to liberation of methacrylic acid, presumably deriving from degradation of those of the dimethacrylates only bonded in the matrix by one end of the molecule. It was estimated that a TEGDMA-polymer will be hydroylzed faster than a BISGMA-polymer. It is proposed that hydrolases in saliva increase the wear rate of composite resin fillings.Keywords
This publication has 5 references indexed in Scilit:
- Release of Formaldehyde from Dental CompositesJournal of Dental Research, 1988
- Correlation between in vitro and in vivo wear of posterior restorative materialsDental Materials, 1987
- Composite degradation in vivoDental Materials, 1986
- Wear rates of posterior composite resinsThe Journal of the American Dental Association, 1986
- P-10 — Its potential as a posterior compositeDental Materials, 1985