Limits of Neurogenesis in Primates
- 1 March 1985
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 227 (4690) , 1054-1056
- https://doi.org/10.1126/science.3975601
Abstract
Systematic analysis of autoradiograms prepared from postpubertal rhesus monkeys given single and multiple injections of tritium-labeled thymidine and killed 3 days to 6 years later displayed a slow turnover of glial cells but failed to reveal any radiolabeled neurons. Therefore, unlike neurons of some nonprimate species, all neurons of the rhesus monkey brain are generated during prenatal and early postnatal life. A stable population of neurons in primates, including humans, may be important for the continuity of learning and memory over a lifetime.This publication has 23 references indexed in Scilit:
- DNA Synthesis and Cell Division in the Adult Primate BrainaAnnals of the New York Academy of Sciences, 1985
- Neurons Generated in the Adult Brain Are Recruited into Functional CircuitsScience, 1984
- An analysis of the time of origin of neurons in the entorhinal and subicular cortices of the catJournal of Comparative Neurology, 1983
- The tectopontine projection in the rat with comments on visual pathways to the basilar ponsJournal of Comparative Neurology, 1981
- Neurogenesis in the 3‐month‐old rat visual cortexJournal of Comparative Neurology, 1981
- Genesis of the dorsal lateral geniculate nucleus in the rhesus monkey: Site and time of origin, kinetics of proliferation, routes of migration and pattern of distribution of neuronsJournal of Comparative Neurology, 1977
- Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light RadioautographsScience, 1977
- An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the ratJournal of Comparative Neurology, 1975
- Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: An autoradiographic analysisJournal of Comparative Neurology, 1973
- Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neuronsJournal of Comparative Neurology, 1973