Studies on the transfer of antibody-producing capacity. I. The transfer of antibody-producing cells to young animals.

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  • 1 April 1959
    • journal article
    • Vol. 2  (2) , 137-47
Abstract
Normal adult spleen cells were antigenically stimulated by incubation with isolated flagella from Salmonella bacteria, and after neutralization of free antigen and washing, were transferred to normal and sublethally X-irradiated mice and rats of various ages by intraperitoneal injection. Neonatal rats and Hall Institute mice could not produce antibody following such injections, but more mature rats and Hall Institute mice, and neonatal C3H mice, could produce antibody.