Atypical Surface Marker Characteristics in a T‐Cell Lymphoma

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Abstract
A case of T[thymus-derived]-cell lymphoma with an unusual phenotype is described. The majority of malignant tumor cells did not form E[sheep erythrocyte]-rosettes, and lacked surface immunoglobulin but reacted with an antiserum to T cells and thymocytes. Localized acid phosphatase and nonspecific .alpha.-naphthol acid esterase activities and a prominent, convoluted, nuclear pattern in some neoplastic cells also supported the T cell derivation. The results demonstrate the importance of using a panel of markers for identification of the cellular derivation of some lymphomas.