A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation
Open Access
- 1 January 2004
- journal article
- research article
- Published by Springer Nature in Theoretical Biology and Medical Modelling
- Vol. 1 (1) , 2
- https://doi.org/10.1186/1742-4682-1-2
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Multiple feedback loops are key to a robust dynamic performance of tryptophan regulation in Escherichia coliFEBS Letters, 2004
- A positive-feedback-based bistable ‘memory module’ that governs a cell fate decisionNature, 2003
- EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagationNature Cell Biology, 2003
- A PI3-Kinase Signaling Code for Insulin-Triggered Insertion of Glucose Transporters into the Plasma MembraneCurrent Biology, 2002
- Hydrogen Peroxide Generated during Cellular Insulin Stimulation Is Integral to Activation of the Distal Insulin Signaling Cascade in 3T3-L1 AdipocytesJournal of Biological Chemistry, 2001
- Insulin signalling and the regulation of glucose and lipid metabolismNature, 2001
- Insulin Receptor Binding Kinetics: Modeling and Simulation StudiesJournal of Theoretical Biology, 2000
- Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.Journal of Clinical Investigation, 1995
- A mathematical model and computer simulation study of insulin sensitive glucose transporter regulationJournal of Theoretical Biology, 1991
- A mathematical model and computer simulation study of insulin receptor regulationJournal of Theoretical Biology, 1991