Decreased Gray Matter in Normal Aging: An in Vivo Magnetic Resonance Study
- 1 January 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Gerontology
- Vol. 47 (1) , B26-B30
- https://doi.org/10.1093/geronj/47.1.b26
Abstract
Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p < .01) and higher percentage of CSF (p < .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matterKeywords
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