Combination Chemotherapy in the Treatment of Metastatic Hemangiopericytoma

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Abstract
A case of hemangiopericytoma of subcutaneous tissue with multiple metastases to the lungs is presented ombined treatment with methotrexate, cyclophosphamide and vincristine sulfate inhibited temporarily the growth of the metastases in the lungs, as shown in growth curves of 3 metastases whose relative volume was estimated from chest roentgenograms. No other treatment employed inhibited the tumor progression. As hemangiopericytoma is considered to be resistant to cytostatic drugs, combination chemotherapy in the treatment of a diffuse metastatic disease is suggested.

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