Speciation of Butyltin Compounds by High-Performance Liquid Chromatography with Inductively Coupled Plasma Mass Spectrometry Detection

Abstract
Inductively coupled plasma mass spectrometry (ICP-MS), used as an element-specific detection method for high-performance liquid chromatography (HPLC), is applied to butyltin speciation. All tin forms are separated via reversed-phase chromatography using 0.1% m/v tropolone in a methanol—water—acetic acid solution (80:14:6 v/v/v) as the mobile phase. The absolute detection limits are 0.15 ng (as tin) for tributyltin and 0.24 ng (as tin) for di- and monobutyltin. Triethyltin is used as an internal standard. Data reported include capacity factors, retention times, reproducibility, and linearity of detection. In addition, the structure of butyltin species as complexes with tropolone has been determined.

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