4 ′‐iodo‐4′‐Deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters
Open Access
- 28 March 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 17 (8) , 803-809
- https://doi.org/10.1096/fj.02-0764com
Abstract
Transthyretin Leu55Pro is one of the most aggressive mutations in familial amyloidotic polyneuropathy, an autosomal dominant disorder characterized by extracellular deposition of fibrillar amyloid pr...Keywords
Funding Information
- Università degli Studi di Pavia
- Fondazione IRCCS Policlinico San Matteo
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