EXPERIMENTAL HYDRONEPHROSIS

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Abstract
The absence of any change in the ordinary rate of development of hydronephrosis when an increased blood flow through the kidney and a unilateral diuresis are produced by splanchnotomy has been experimentally demonstrated.1 The present paper considers the effects on the rate of development of hydronephrosis of a diminished blood flow but increased intrarenal pressure and oliguria, brought about by partial obstruction of the renal vein. Partial constriction of the renal vein causes a capillary stasis and an increase in glomerular pressure which may rise in proportion to the degree of obstruction, "until with complete closure it may reach that of the renal artery" (Cushny). Despite this rise of pressure in the glomerulus, the amount of urine filtered through is diminished in indirect ratio to the amount of obstruction. The diminished blood flow has the predominant effect. But, with partial obstruction, will the rise in glomerular pressure, even though

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