Agranulocytosis during malaria prophylaxis with Maloprim (pyrimethamine and dapsone)

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Abstract
Summary: A case of agranulocytosis during malaria prophylaxis with Maloprim (pyrimethamine and dapsone) is described. At the recommended dose of one tablet weekly this is apparently a rare occurrence but highlights one of the hazards in a changing climate of malarial prophylaxis in which the use of Maloprim is increasing.