Ochrindoles A-D: New Bis-Indolyl Benzenoids from the Sclerotia of Aspergillus ochraceus NRRL 3519
- 1 May 1994
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 57 (5) , 634-639
- https://doi.org/10.1021/np50107a011
Abstract
Four new prenylated bis-indolyl benzenoid metabolites (ochrindoles A-D; 1-4) were isolated from antiinsectan organic extracts of the sclerotia of Aspergillus ochraceus (NRRL 3519). The structures of these compounds were determined primarily through HMBC, selective INEPT, and NOESY experiments. These compounds displayed moderate activity in feeding assays against the corn earworm Helicoverpa zea and the driedfruit beetle Carpophilus hemipterus. Compounds 1-4 also exhibited activity against Gram-positive bacteria.Keywords
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