The evolution of synthetic oral drug properties
- 1 February 2005
- journal article
- review article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (4) , 1087-1090
- https://doi.org/10.1016/j.bmcl.2004.12.024
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Time-Related Differences in the Physical Property Profiles of Oral DrugsJournal of Medicinal Chemistry, 2004
- Characteristic Physical Properties and Structural Fragments of Marketed Oral DrugsJournal of Medicinal Chemistry, 2003
- A Comparison of Physiochemical Property Profiles of Development and Marketed Oral DrugsJournal of Medicinal Chemistry, 2003
- Molecular Properties That Influence the Oral Bioavailability of Drug CandidatesJournal of Medicinal Chemistry, 2002
- Drug-like properties and the causes of poor solubility and poor permeabilityJournal of Pharmacological and Toxicological Methods, 2000
- Property distribution of drug-related chemical databases*Journal of Computer-Aided Molecular Design, 2000
- Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP MethodsThe Journal of Physical Chemistry A, 1998
- Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews, 1997