GLUCOSE-GLUCAGON RELATIONSHIPS IN ADULT SHEEP

  • 1 January 1977
    • journal article
    • research article
    • Vol. 41  (1) , 95-97
Abstract
Glucose-glucagon relationships were examined in adult sheep. Hyperglycemia was induced by infusing glucose at 120 mg/h per kg body wt. Hypoglycemia was obtained by infusing insulin at 1.2 U/h. In several experiments glucose at 40 mg/h per kg was infused with insulin to obtain hyperinsulinemia without hypoglycemia to distinguish glucose-insulin effects. Glucagon concentrations decreased during hyperglycemia and increased during hypoglycemia. Glucose-glucagon interactions may be important in regulation of glucagon secretion in sheep.