Application of Derivative Spectroscopy to the Determination of Plasma Theophylline in the Presence of Phenobarbital
- 1 March 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 9 (2) , 76-80
- https://doi.org/10.1093/jat/9.2.76
Abstract
A rapid, simple, and sensitive procedure for the determination of theophylline in plasma using second derivative spectroscopy is described. Second derivative spectra of plasma extracts containing theophylline in concentrations ranging from 2 to 20 µg/mL were studied. The method is suitable for the measurement of plasma theophylline in patients treated for cardiorespiratory disorders. Interference from other compounds such as phenobarbital can be avoided.This publication has 7 references indexed in Scilit:
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