Factor X Deficiency and Systemic Amyloidosis

Publisher Website
Google Scholar
Abstract
The association of an isolated acquired factor X (Stuart-factor) deficiency and systemic acquired amyloidosis has been sporadically reported over the last 15 years,1 , 2 and over two thirds of the patients with acquired factor X deficiency have systemic amyloidosis. These facts suggest that an important relation exists between the two entities. In view of the isolated nature of the factor X deficiency it does not appear reasonable to implicate hepatocellular destruction by amyloid infiltrates as the causative mechanism, since most patients with acquired factor X deficiency have normal levels of other coagulation factors known to be of hepatocellular origin. In addition, . . .