A temperature sensitive nonsense mutation affecting the synthesis of a major protein of Escherichia coli K12
- 1 June 1975
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 139 (2) , 167-176
- https://doi.org/10.1007/bf00264696
Abstract
A temperature sensitive nonsense (TSN) mutant of E. coli K12 has been isolated in which a major bacterial protein is not synthesized at 42° C. This protein is found in the parental strain at 42° C and in cells rendered temperature resistant due to the insertion of a number of different nonsense suppressors or the normal allele of the mutant locus.Keywords
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