In vivo Conversion of 7α-Hydroxycholesterol-14C to 3β, 7α-Dihydroxychol-5-enoic-14C and -4-enoic-14C Acids as well as to Allocholic-14C Acid in the Hen
- 1 January 1972
- journal article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 71 (1) , 77-83
- https://doi.org/10.1093/oxfordjournals.jbchem.a129748
Abstract
It was demonstrated that 7α-hydroxycholesterol-14C administered to a hen furnished with a bile-fistula was converted not only to the common primary bile acids but also to 3β, 7α-dihydroxychol-5- and -4-enoic acids, the latter of which has recently been isolated from bladder bile of hens. As a metabolite of the 7α-hydroxy sterol-14C, allocholic acid was also identified and its natural occurrence in bladder bile once reported was confirmed (see “RESULTS”).Keywords
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