OESTROGEN TREATMENT AND SUBSEQUENT PREGNANCY IN TWO PATIENTS WITH SEVERE HYPERGONADOTROPHIC OVARIAN FAILURE

1 September 1978

journal article
research article
Published by Oxford University Press (OUP) in Acta Endocrinologica

Vol. 89 (1) , 149-157
https://doi.org/10.1530/acta.0.0890149

Abstract

This report describes in detail the histological and hormonal findings in a patient with Turner''s syndrome (45,XO) and a patient with premature menopause (46,XX), who both conceived after withdrawal or reduction of substitution therapy with estrogens. The etiology of severe hypergonadotropic ovarian failure is discussed, and theories regarding a possible relationship between the estrogen treatment and subsequent pregnancy are hypothesized.

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