Blood Thrombotest Versus Prothrombin Test

Publisher Website
Google Scholar
Abstract
THE BASIC requirement for anticoagulation with bishydroxycoumarin (Dicumarol) or an analogue is a good laboratory test for the effect of the drug upon the coagulation mechanism of the blood. The Quick1 prothrombin test expressed in time or per cent has been relied on in the past to regulate the dose of bishydroxycoumarin. Evidence has accumulated recently, however, to indicate that these drugs suppress the proconvertin (Factor VII) content of the blood to a greater extent than they suppress the prothrombin (Factor II) content,2 as well as suppressing Factor IX (Christmas factor) and Factor X (Stuart factor) to a variable degree. It is desirable, therefore, to have a simple method which will test for all of these factors in patients receiving bishydroxycoumarin or an analogue. The thrombotest of Owren3 is devised for this purpose and is reported to test for the factors (II, VII, IX, and X) that

This publication has 0 references indexed in Scilit: