A Glial Spin on Neurotrophins
- 8 November 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 298 (5596) , 1184-1186
- https://doi.org/10.1126/science.1078709
Abstract
Glial cells in the nervous system are responsible for ensheathing the axons of neurons in myelin. However, the positive and negative signals regulating myelination remain obscure. In a Perspective, Hempstead and Salzer discuss new work (Cosgaya et al.) that identifies the neurotrophin BDNF and its receptor p75 as positive modulators of myelination by Schwann cells in the peripheral nervous system.Keywords
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