Abstract
A patient developed benign nodular hyyerplasia of the liver after long-term, high-dose estrogen therapy. A 10.5 cm benign liver nodule appeared after 3 yr of high-dose estrogen therapy and was resected. Fourteen months later while still receiving estrogen, a 4.5 cm nodule and multiple small nodules were seen on angiography. Four months after estrogen was discontinued, the large liver nodule disappeared and the smaller ones decreased.