NINETEEN PARACENTRIC CHROMOSOMAL INVERSIONS IN MICE
Open Access
- 1 January 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 76 (1) , 109-117
- https://doi.org/10.1093/genetics/76.1.109
Abstract
Using mutagens on sperm and spermatids we have produced nineteen chromosomal inversions in mice. The levels of radiation and chemical mutagen we used induced inversions in about one per cent of the animals screened. Nine inversions have been transmitted through successive generations, and the particular frequency of first meiotic anaphase bridges manifested by each inversion remained constant. The cytological properties of first meiotic anaphases varied considerably among the inversions. Chromosomal locations of five inversions are known. Four of the five are fully viable in homozygous condition.Keywords
This publication has 1 reference indexed in Scilit:
- Producing and detecting paracentric chromosomal inversions in miceMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1971