EVIDENCE FOR A PARTICLE-ASSOCIATED RNA-DIRECTED DNA-POLYMERASE IN RABBIT PLACENTAL AND UTERINE TISSUES

  • 1 January 1976
    • journal article
    • research article
    • Vol. 36  (12) , 4687-4692
Abstract
A RNA-directed DNA polymerase associated with particles that band at a density characteristic of type C RNA viruses was found in normal rabbit placental and uterine tissues taken during the early stages of gestation. That the rabbit RNA-directed DNA polymerase is distinct from the known cellular DNA polymerases and similar to the RNA-directed DNA polymerase of mammalian type C RNA viruses is shown by column chromatographic characteristics, template primer preferences, molecular weight determination and an absolute requirement for the divalent cations.