ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways
Open Access
- 20 March 1998
- journal article
- research article
- Published by Elsevier
- Vol. 92 (6) , 725-734
- https://doi.org/10.1016/s0092-8674(00)81401-4
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Mdm2 promotes the rapid degradation of p53Nature, 1997
- mdm-2 Inhibits the G1 Arrest and Apoptosis Functions of the p53 Tumor Suppressor ProteinMolecular and Cellular Biology, 1996
- Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53Nature, 1995
- Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.Genes & Development, 1994
- Cyclins and cancer II: Cyclin D and CDK inhibitors come of ageCell, 1994
- Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential.Genes & Development, 1994
- Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.Proceedings of the National Academy of Sciences, 1994
- Mapping of the p53 and mdm-2 interaction domains.Molecular and Cellular Biology, 1993
- Functional interactions of the retinoblastoma protein with mammalian D-type cyclinsCell, 1993
- A novel genetic system to detect protein–protein interactionsNature, 1989