Protriptyline treatment of sleep hypoxaemia in Duchenne muscular dystrophy.
Open Access
- 1 December 1989
- Vol. 44 (12) , 1002-1005
- https://doi.org/10.1136/thx.44.12.1002
Abstract
Protriptyline 20 mg daily reduced the total time spent in rapid eye movement sleep in an open study in four subjects with Duchenne muscular dystrophy. Sleep related hypoxaemia and episodes of desaturation were reduced. Anticholinergic side effects were prominent, however, in these patients, precluding its use for regular treatment.This publication has 7 references indexed in Scilit:
- Hypoxemia during Sleep in Duchenne Muscular DystrophyAmerican Review of Respiratory Disease, 1988
- Effects of protriptyline on sleep related disturbances of breathing in restrictive chest wall disease.Thorax, 1986
- DIFFERENTIAL ELEVATION BY PROTRIPTYLINE AND DEPRESSION BY DIAZEPAM OF UPPER AIRWAY RESPIRATORY MOTOR-ACTIVITYPublished by Elsevier ,1985
- The Effects of Protriptyline in Sleep-Disordered Breathing1,2American Review of Respiratory Disease, 1983
- Protriptyline in the treatment of sleep apnoea.Thorax, 1982
- Sleep apneaNeurology, 1979
- A Review of the Cardiovascular Effects and Toxicity of Tricyclic AntidepressantsPsychosomatic Medicine, 1975