Allergic contact dermatitis from pyoctanin

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Abstract
Although pyoctanin is widely used in medicine, there are hardly any reports of contact allergy to it. Most reports of side‐effects refer to irritant reactions after topical application. We describe 2 patients who developed pyoctanin contact dermatitis after long‐term application on damaged skin, Positive patch test results down to concentrations of 0.0025% and 0.05% aqueous pyoctanin solution, respectively, were found.