Novel enantioselective reaction of diketene with aldehydes promoted by chiral Schiff base–titanium alkoxide complex
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 3,p. 341-342
- https://doi.org/10.1039/c39940000341
Abstract
Reaction of a variety of aldehydes with diketene in the presence of chiral Schiff base–titanium alkoxide complexes proceeds with high enantioselectivity to afford the corresponding 5-hydroxy-3-oxoesters.Keywords
This publication has 16 references indexed in Scilit:
- Enantioselective Addition of Organometallic Reagents to Carbonyl Compounds: Chirality Transfer, Multiplication, and AmplificationAngewandte Chemie International Edition in English, 1991
- A new strategy for the synthesis of mevinic acid analoguesTetrahedron Letters, 1990
- Asymmetric Synthesis Utilizing External Chiral LigandsSynthesis, 1990
- A Facile Chiral Synthesis of the Lactone Moiety of Compactin and Mevinolin from (R)-O-BenzylglycidolSynthesis, 1989
- Synthesis of a chiral synthon for the lactone portion of compactin and mevinolinTetrahedron Letters, 1988
- Asymmetric synthesis via acetal templates. 15. The preparation of enantiomerically pure mevinolin analogsTetrahedron Letters, 1988
- Enantioselective Synthesis with Optically Active Transition-Metal CatalystsSynthesis, 1988
- Synthesis of an HMG-CoA reductase inhibitor; a diastereoselective aldol approachTetrahedron Letters, 1987
- The synthesis of mevinic acidsTetrahedron, 1986
- ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.The Journal of Antibiotics, 1976