Effect of Interferon on the Accumulation of RNA Transcripts of Genes Coding for Cellular and Viral Proteins
- 1 May 1989
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 70 (5) , 1267-1271
- https://doi.org/10.1099/0022-1317-70-5-1267
Abstract
Using plasmids containing sequences complementary to the genes that code for oligo-2'',5''-adenylate synthetase, actin and H4 histone, we have shown that although interferon does not affect the accumulation of RNA transcripts of the actin and H4 histone genes, it activates the accumulation of RNA transcripts of the oligo-2'',5''-adenylate synthetase gene. However, interferon inhibits the accumulation of RNA transcripts of simian virus 40 (SV40) genes in SV40-infected cells.This publication has 10 references indexed in Scilit:
- UV crosslinking of RNA to nylon membrane enhances hybridization signalsMolecular Biology Reports, 1986
- Structure of two forms of the interferon-induced (2′-5′) oligo A synthetase of human cells based on cDNAs and gene sequences.The EMBO Journal, 1985
- Molecular cloning and sequence of partial cDNA for interferon-induced (2'-5')oligo(A) synthetase mRNA from human cells.Proceedings of the National Academy of Sciences, 1983
- Mechanism of interferon action Differential effect of interferon on the synthesis of simian virus 40 and reovirus polypeptides in monkey kidney cellsVirology, 1982
- The actin genes of drosophila: a dispersed multigene familyCell, 1980
- An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.Proceedings of the National Academy of Sciences, 1979
- Interferon, double-stranded RNA, and RNA degradation: activation of an endonuclease by (2'-5')An.Proceedings of the National Academy of Sciences, 1979
- The differential effect of interferon on T antigen production in simian virus 40-infected or transformed cellsVirology, 1979
- Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.Proceedings of the National Academy of Sciences, 1978
- Mechanism of Interferon Action: Further Evidence for Transcription as the Primary Site of Action in Simian Virus 40 InfectionJournal of General Virology, 1976