Regulation of ion transport by protein–protein interaction domains
- 1 September 1997
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Nephrology and Hypertension
- Vol. 6 (5) , 447-454
- https://doi.org/10.1097/00041552-199709000-00007
Abstract
Protein-protein interaction via specific modular domains has been implicated in the regulation of many signalling pathways. Recently, such modules, in particular WW, Src homology-3 and PDZ domains, have been shown to regulate localization, clustering and function of several ion channels and transporters, including the epithelial Na+ channel, K+ channel and ionotropic neurotransmitter receptors.Keywords
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