Enzymology of Experimental Liver Disease in Marmoset Monkeys

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Abstract
The activities of lactate dehydrogenase, isocitrate dehydrogenase, malate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, glutamate dehydrogenase, glucose-6-phosphate dehydrogenase, phosphogluconate dehydrogenase and creatine phosphokinase were determined in extracts from liver (cytoplasmic and mitochondrial compartments), other organs and in serum of healthy, wild caught, laboratory acclimatized marmosets (Saguinus species). The data were to serve as baseline and control values for the study of experimental liver diseases. Striking species differences were found when the activity levels and enzyme patterns of liver and serum were compared to data of man, horse, dog, guinea pig, rat and mouse.

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