Purging Tumor Cells From Bone Marrow by Use of Antibody and Complement: A Critical Appraisal

6 April 1988

journal article
review article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 80 (3) , 154-159
https://doi.org/10.1093/jnci/80.3.154

Abstract

This review highlighted several problems associated with the use of antibody and complement in the elimination of tumor cells from bone marrow that was to be used for transplantation, and it discussed some of the difficulties encountered in developing this approach in model systems. These problems should be seriously considered by any clinician contemplating this method for bone marrow purging. [J Natl Cancer Inst 1988;80:154-159]

Keywords

COMPLEMENT SYSTEM PROTEINS
ANTIBODIES
BONE MARROW
TUMOR CELLS
PURGING
EXCRETORY FUNCTION
CANCER
BONE MARROW PURGING
TRANSPLANTATION