American Red Cross experience with routine testing for hepatitis B core antibody
- 1 March 1989
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 29 (3) , 230-232
- https://doi.org/10.1046/j.1537-2995.1989.29389162729.x
Abstract
The implementation of routine testing of blood donations for hepatitis B core antibody (anti-HBc) has allowed the characterization of the performance of the test in a large number of samples from apparently healthy individuals. This study reports the experience of the American Red Cross in testing 2.3 million donors for anti-HBc. The test protocol reproducibly identified a distinct population of donors. The anti-HBc-positive rate varied by region of the continental United States and by the time of year. In a case-control study, 85 percent of subsequent donations from anti-HBc-positive donors were anti-HBc positive. The predictions made in an earlier pilot study regarding the performance and impact of the test were borne out.This publication has 5 references indexed in Scilit:
- Significance of isolated antibody to hepatitis B core antigen determined by immune response to hepatitis B vaccinationJAMA, 1987
- Hepatitis B core antibody (anti-HBc) in blood donors in the United States: implications for surrogate testing programsTransfusion, 1987
- Specificity of enzyme immunoassay for hepatitis B core antibody used in screening blood donorsTransfusion, 1987
- Antibody to Hepatitis B Core Antigen as a Paradoxical Marker for Non-A, Non-B Hepatitis Agents in Donated BloodAnnals of Internal Medicine, 1986
- Hepatitis B Virus Antibody in Blood Donors and the Occurrence of Non-A, Non-B Hepatitis in Transfusion RecipientsAnnals of Internal Medicine, 1984