Mater, a maternal effect gene required for early embryonic development in mice
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- 1 November 2000
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 26 (3) , 267-268
- https://doi.org/10.1038/81547
Abstract
Maternal effect genes produce mRNA or proteins that accumulate in the egg during oogenesis. We show here that Mater, a mouse oocyte protein dependent on the maternal genome, is essential for embryonic development beyond the two-cell stage. Females lacking the maternal effect gene Mater are sterile. Null males are fertile.Keywords
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