Liquid Chromatographic Analysis of Bile Acid Methyl Esters

Abstract
Methods have been developed for the qualitative and quantitative analysis of hydroxy and keto derivatives of methyl cholanates utilizing a ¼″ by 1′ μPorasil column, various mixtures of hexane and ethyl acetate and a refractive index detector. The system has been calibrated for some of the methyl dihydroxycholanates using 3α;,7α-dihydroxy-12-oxocholanate as an internal standard and applied to the analysis of the mixtures of diols resulting from the reduction of methyl 3,12-dioxocholanate with NaBH4 and with Raney nickel.

This publication has 1 reference indexed in Scilit: