Blood Sugar and Diabetic Complications

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Abstract
To the Editor: The question of whether diabetic complications are related to the degree of control of blood sugar is an important and still controversial one.1 , 2 In 1947 we began a long-term prospective study aimed at answering that question. We have been studying 4400 diabetic patients (2800 of them have been personally followed from the onset of their disease) for as long as 25 years. The degree of control of blood sugar has been evaluated by circadian blood sugar values obtained at intervals of two to four months, and from continuous daily diaries of urine tests done at home. Each . . .