Effect of Some Self-Selection Conditions on the Voluntary Alcohol Intake of Rats

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Abstract
Expts.are performed on rats depleted of Factor N1 with a voluntary alcohol intake stabilized at 10% V/V soln. Self-selection of solid sucrose and of the nonsucrose moiety of the basic diet significantly decreased, the proportion of sucrose ingested and did not change the intake of alcohol. A dietary supplement of dried liver induced a decreased alcohol intake in most of the animals, uncorrelated with changes in the intake of solid food. Changes in the proportion of sucrose in the diet from 64% to 81% and to 29% did not significantly alter the intake of alcohol. Offering choice of a 3d fluid in the form of sucrose or dextrose solns induced a significant decrease of the alcohol intake in all the rats. Concentrations of the sugar solutions ranging from 10 to 70% did not differ in their influence on alcohol intake. This decrease in the alcohol intake is significantly correlated with the extra intake of sucrose (r = -0.512 and P < 0.01) but not with the extra intake of fluid (r = -0.066). Offering as a 3d choice a solution of pure B vitamins, for which rats exhibit a clear preference, did not significantly change alcohol intake.

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