4(1H)-Quinolinone Alkaloids. An Efficient Synthesis of Graveoline by Palladium-Catalysed ReductiveN-Heterocyclisation
- 1 February 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (3) , 495-501
- https://doi.org/10.1080/00397919608003640
Abstract
An efficient synthesis of the 4H-quinolone alkaloid graveoline has been achieved by a route featuring an Pd(II)-catalysed reductive N-hetero-cyclisation [CO(3 MPa), Pd(TMB)2, TMPhen, 170°C, 3h] of 2′-nitrochalcone as a key step.Keywords
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