IMAGING OF SPONTANEOUS CANINE TUMORS WITH AMMONIA AND L-GLUTAMINE LABELED WITH N-13

  • 1 January 1977
    • journal article
    • research article
    • Vol. 18  (7) , 718-723
Abstract
Ammonia and L-glutamine, labeled with 13N, were tested as imaging agents for a variety of spontaneous canine tumors. The imaging capabilities of these compounds were compared with each other, other scanning agents, and radiologic and pathologic procedures. Good agreement between positive .gamma.-images and postmortem findings occurred in 11 of 15 cases with [13N] ammonia as the localizing agent. Eight of the 9 scans using [13N] glutamine as the imaging agent showed positive correlation with postmortem findings. In cases where ammonia and glutamine were used to image the same lesion, no qualitative differences in tumor uptake were found between the two.