ADULT-ONSET STILLS DISEASE

  • 1 January 1979
    • journal article
    • research article
    • Vol. 120  (12) , 1507-1511
Abstract
Four adults with an illness similar to the systemic variant of juvenile rheumatoid arthritis in children (Still''s disease) were described. All 4 had fever, an erythematous maculopapular rash, splenomegaly and arthritis. The arthritis was asymmetric and involved only a few joints simultaneously. Erosive arthritis developed in 1 patient. Three patients had a sore throat; 2 had pleurisy and pericarditis; and 1 had transient abnormalities of liver function. The laboratory features included anemia, leukocytosis and high leukocyte counts in the synovial fluid. High titers of rubella hemagglutination-inhibiting antibody were detected in 2 patients, 1 of whom had rubella virus in the urine. Only 1 patient responded well to therapy with acetylsalicylic acid; the other 3 were given prednisone therapy, and 2 still require it.

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