Schistosoma mansoni surface antigen defined by a rat monoclonal IgG2a.
Open Access
- 1 November 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 129 (5) , 2232-2234
- https://doi.org/10.4049/jimmunol.129.5.2232
Abstract
A schistosomula surface antigen of 38,000 daltons has been isolated by using a rat monoclonal IgG2a that has been shown to confer protection against S. mansoni infection by passive transfer in rats. This antigen is one of the previously characterized surface proteins reacting with sera from various infected hosts, including rat, mouse, monkey, and human. Studies on parasites of different developmental stages indicated the presence of this antigen on cercariae and skin-derived or mechanically transformed schistosomula.This publication has 3 references indexed in Scilit:
- Schistosoma mansoni: Rapid isolation and purification of schistosomula of different developmental stages by centrifugation on discontinuous density gradients of PercollExperimental Parasitology, 1982
- Surface antigens of Schistosoma mansoniMolecular and Biochemical Parasitology, 1981
- Eosinophil‐dependent cytotoxicity in rat schistosomiasis. Involvement of IgG2a antibody and role of mast cellsEuropean Journal of Immunology, 1978