Presence of Integron-Associated Resistance in the Community Is Widespread and Contributes to Multidrug Resistance in the Hospital
- 1 August 2002
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 40 (8) , 3038-3040
- https://doi.org/10.1128/jcm.40.8.3038-3040.2002
Abstract
Integrons are strongly associated with the multidrug resistance seen in gram-negative bacilli in the hospital environment. No data, however, are available on their prevalence in the community. This study is the first to show that integrons are widespread in Enterobacteriaceae in the community and that integron-associated resistance genes in the community constitute a substantial reservoir for multidrug resistance in the hospital.Keywords
This publication has 11 references indexed in Scilit:
- Novel Gene Cassettes and IntegronsAntimicrobial Agents and Chemotherapy, 2001
- Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restrictionThe Lancet, 2001
- Characterization of Salmonella enterica Serovar Typhimurium DT104 Isolated from Denmark and Comparison with Isolates from Europe and the United StatesJournal of Clinical Microbiology, 2000
- Incidence and Characterization of Integrons, Genetic Elements Mediating Multiple-Drug Resistance, in Avian Escherichia coliAntimicrobial Agents and Chemotherapy, 1999
- Resistance gene captureCurrent Opinion in Microbiology, 1999
- Characterization of Integrons inEscherichia coliof the Normal Intestinal Flora of SwineMicrobial Drug Resistance, 1999
- Class I integrons in Gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compoundsJournal of Antimicrobial Chemotherapy, 1998
- Antibiotic resistance in gram-negative bacteria: the role of gene cassettes and integronsDrug Resistance Updates, 1998
- PCR mapping of integrons reveals several novel combinations of resistance genesAntimicrobial Agents and Chemotherapy, 1995
- Genetic analyses of sulfonamide resistance and its dissemination in gram-negative bacteria illustrate new aspects of R plasmid evolutionAntimicrobial Agents and Chemotherapy, 1991