RETINAL INVOLVEMENT IN MORQUIOS SYNDROME (MPS-IV)

  • 1 January 1985
    • journal article
    • research article
    • Vol. 17  (6) , 349-354
Abstract
Prior to this report, pigmentary degeneration of the retina had been described in 4 of the 6 types of mucopolysaccharidosis (MPS). However, it had not been described in Morquio''s syndrome. The case presented apparently represents the 1st patient with Morquio''s syndrome demonstrating ophthalmoscopic and electrophysiologic abnormalities. The patient demonstrated arteriolar narrowing, as well as an increased photopic b-wave implicit time, decreased scotopic b-wave amplitude, and a slightly abnormal electro-oculogram (EOG). At 43 yr of age, this patient represents the oldest individual with Morquio''s syndrome tested electorphysiologically. The retinal involvement in the disease evidently is mild but progressive and therefore perhaps is not seenin younger patients but becomes apparent in older persons with Morquio''s syndrome.

This publication has 3 references indexed in Scilit: