ENANTIOFACE-DIFFERENTIATING (ASYMMETRIC) ADDITION OF ALKYLLITHIUM TO ALDEHYDES BY USING (2S, 2′S)-2-HYDROXYMETHYL-1-[(1-METHYLPYRROLIDIN-2-YL)METHYL] PYRROLIDINE AS CHIRAL LIGAND
- 5 February 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 7 (2) , 219-222
- https://doi.org/10.1246/cl.1978.219
Abstract
Optically active alcohols are produced in good optical yields by treating aromatic and aliphatic aldehydes with alkyllithium by using (2S, 2′S)-2-hydroxymethyl-1-[(1-methylpyrrolidin-2-yl)methyl]pyrrolidine as chiral ligand.Keywords
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