The use of kinetic-dynamic interactions in the evaluation of drugs

This publication has 100 references indexed in Scilit:

• Pharmacokinetic modeling of the anticonvulsant response of oxazepam in rats using the pentylenetetrazol threshold concentration as pharmacodynamic measure
  Journal of Pharmacokinetics and Biopharmaceutics, 1988
• Pharmacodynamics of Triazolam After Intravenous Administration
  The Journal of Clinical Pharmacology, 1987
• Relationships Between CSF Drug Concentrations, Receptor Binding Characteristics, and Pharmacokinetic and Pharmacodynamic Properties of Selected 1,4-Substituted Benzodiazepines
  Clinical Pharmacokinetics, 1987
• Pharmacodynamic modeling of the EEG effects of ketamine and its enantiomers in man
  Journal of Pharmacokinetics and Biopharmaceutics, 1987
• Integrated Pharmacokinetic-Dynamic Modeling of Drugs Acting on the CNS
  Drug Metabolism Reviews, 1984
• Benzodiazepine receptors': Correlation with pharmacological responses in living animals
  Life Sciences, 1982
• Understanding the Dose-Effect Relationship
  Clinical Pharmacokinetics, 1981
• The antagonistic effects of 5-ethyl-5-(3-hydroxy-1-methylbutyl)-barbituric acid on pentobarbital narcosis in both naïve and tolerant mice
  Life Sciences, 1978
• Increase of hexobarbital sleeping time and inhibition of drug metabolism by the major metabolite of diphenylhydantoin
  Life Sciences, 1974
• Kinetics of pharmacologic response I. Proposed relationships between response and drug concentration in the intact animal and man
  Journal of Theoretical Biology, 1968