GENETIC CONTROL OF C3 PRODUCTION BY THE S REGION OF THE MOUSE MHC

Abstract
SUMMARY: The present paper reports evidence indicating that the level of the third complement component (C3) is regulated by the S region of the murine H‐2 complex. In fact, using congenic strains of mice we demonstrate that mice with the k haplotype at the S region show high C3 levels, whereas mice with the d haplotype at the S region show low C3 levels.