Effects of Total-Body Irradiation on the Production of Antibody in Man

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Abstract
THE numerous studies of the effects of whole-body irradiation on the immunologic response of animals have recently been reviewed,1 and attention has been called to the various factors involved in suppressing or delaying the production of antibody by this agent. These include the following: the amounts of antigen and radiation used; the relation of the time of administration of antigen to the administration of radiation; the type and rate of disappearance of the antigen; the type of response tested — that is, primary or secondary; and perhaps variation in the reaction of different species. In general, the anamnestic response is . . .

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